|ABC||Incredible Sunday (Oct.)||Mission: Impossible (Oct.)||The ABC Sunday Night Movie|
|CBS||60 Minutes||Murder, She Wrote||The CBS Sunday Night Movies|
|FOX||21 Jump Street||America's Most Wanted||Married... with Children||It's Garry Shandling's Show||The Tracey Ullman Show||Duet||Local|
|NBC||The Magical World of Disney (Oct.)||Family Ties||Day by Day||NBC Sunday Night at the Movies|
|ABC||MacGyver||Monday Night Football|
|CBS||Newhart||Coming of Age||Murphy Brown (Nov.)||Designing Women||Almost Grown (Nov.)|
|NBC||ALF||The Hogan Family||NBC Monday Night at the Movies|
Note: CBS aired local and paid political programming Sept. and Oct.
|ABC||Who's the Boss?||Roseanne (Oct.)||Moonlighting||thirtysomething|
|CBS||High Risk(Oct 4, 1988 only) / Local and paid political programming (Oct 11-Nov 1) / TV 101 (Nov.)||The CBS Tuesday Night Movies|
|NBC||Matlock||In the Heat of the Night||Midnight Caller (Nov.)|
Note: On NBC, NBC Tuesday Night at the Movies often aired 8-10 p.m. or 9-11 p.m. from September through November. Moonlighting went on hiatus in February 1989, and returned on Sundays in April.
|ABC||Growing Pains||Head of the Class||The Wonder Years||Hooperman||China Beach|
|CBS||The Van Dyke Show (Oct.)||Annie McGuire (Oct.)||The Equalizer||Wiseguy|
|NBC||Unsolved Mysteries (Sep.)||Night Court||Baby Boom (Sep./Nov.) / My Two Dads(Jan.)||Tattingers (Oct.)|
Note: On CBS, Live! With Dick Clark aired 8-9 p.m. in September. On NBC, various specials aired 9:30-10 p.m. from September till November. Then on January 11th the second season of My Two Dads premiered. On ABC, Anything But Love premiered at 9:30 in March 1989.
|CBS||48 Hours||Paradise (Oct)||Knots Landing|
|NBC||The Cosby Show||A Different World||Cheers||Dear John (Oct.)||L.A. Law|
Note: On ABC, various specials and The ABC Thursday Night Movie aired 8-11 p.m. from September till early November. On CBS, CBS Special Movie aired 9-11 p.m. in September till mid-October.
|ABC||Perfect Strangers||Full House||Mr. Belvedere||Just the Ten of Us||20/20|
|CBS||Beauty and the Beast||Dallas||Falcon Crest|
|NBC||Something is Out There (Oct.)||Miami Vice||Rage Hard(Apr. 1989)|
|ABC||Murphy's Law (Dec.)||Police Story (Oct.)|
|CBS||Dirty Dancing (Oct.)||Raising Miranda (Nov.)||Simon & Simon||West 57th|
|NBC||227||Amen||The Golden Girls||Empty Nest (Oct.)||Hunter|
Note: On ABC, the limited-run series Crime of the Century aired in October and Trackdown in November, both 8-9 p.m. On CBS, Live! With Dick Clark, retitled to Dick Clark Presents, moved from Wednesday in September to Saturday for October and aired at 8-9 p.m.